Programme

Registration

Session 1
Cell signalling in cancer (I)

Chair: Sara Sigismund (Milan)

Federica Fusella (Turin)

Morgana: a novel player in apoptotic resistance and metastatic progression in breast cancer cells

Laura Maiorino (Milan)

The COP9 Signalosome is a new repressor of the biological barrier against liver tumorigenesis

Arcangela Gabriella Manente (Novara)

Estrogen receptor β severely impairs mitochondrial functions in human malignant pleural mesothelioma

Alessandro Zannini (Trieste)

Notch1 and notch4 require pin1 to elude the tumor suppressor barrier imposed by fbxw7α in breast cancer

Sara Chiaretti (Milan)

Regulation of tumor cell migration and invasion by the adaptor protein liprin-α1

Giuseppina Votta (Naples)

Modulation of cell migration and matrix remodeling by c-Myc expression in an immortalized human epithelial cell line

Simone Polvani (Florence)

COUP-TFII downregulation inhibits pancreatic cancer growth

Coffee break

Poster Session

Plenary Lecture

Chairs: Annarosa Arcangeli and Lucio Luzzatto (Florence)

Piero Crespo (Santander, Spain)

New concepts for inhibitors of Ras-ERK signals

Dinner

Poster Session

Chair: Annarosa Arcangeli (Florence)

Session 2
Cell signalling in cancer (II)

Chair: Laura Moro (Novara)

Tullio Genova (Turin)

Arachidonic Acid-mediated tumor vascularization: signal transduction and TRP channels balance

Lucia Napione (Turin)

Unraveling the influence of endothelial cell density on VEGF-A signaling

Mario Chiariello (Siena)

Signaling by the ERK8 MAP kinase in autophagy and cancer

Claudia Iavarone (Milan)

New insights into the role of the endocytic protein Epsin3 in breast cancer

Session 3
Cell signalling in the control of gene expression

Chair: Mauro Torti (Pavia)

Giulia Bon (Rome)

p73 sustains chemoresistance in anaplastic thyroid tumors by inducing β4 integrin-dependent PI3K/Akt survival pathway

Maurizio Risolino (Naples)

The transcription factor Prep1 triggers the epithelial to mesenchymal transition by modulating the sensitivity of A549 cells to TGF-β

Viviana di Giacomo (Chieti-Pescara)

PKC α mediated specific gene expression occurs in the inflammatory and stress response of human gingival fibroblasts to 2-hydroxyethyl methacrylate

Michela Palmisano (Milan)

Modulating the teratogenic potential of the mouse embryonic stem cells (ESC)

Mauro Prato (Turin)

Malarial pigment activates p38 MAPK and NF-kappaB pathways in human monocytes: effects on degranulation and inflammatory response

Coffee break

Session 4
Cell signalling in the control of cell differentiation and development

Chair: Guido Tarone (Turin)

Irene Franco (Turin)

Class II PI3K-C2α: a novel regulator of vesicular trafficking at the base of the primary cilium

Giusy Tornillo (Turin)

Role of p130Cas in the control of epithelial cell commitment and differentiation in the mammary gland

Gianni Guidetti (Pavia)

Regulation of the guanine nucleotide exchange factor CalDAG-GEFI by protein kinase A

Benedetta Cerruti (Candiolo, Turin)

Geometry, topology, and out-of-equilibrium dynamics in epithelial morphogenesis

Monika Pema (Milan)

The role of mTORC1 in renal cyst formation and transformation

Lunch

Visit to the Benozzo Gozzoli Chapel
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